PT-141 — 10mg
144.99€
hCG — 10,000iu
The FDA-approved hormone that directly stimulates testicular testosterone production and preserves fertility.
279.99€
Ex Tax 279.99€
- In Stock
- Evidence tier: Established
- Format: Lyophilized
- Purity: 99.5%
- Vial size: 10,000iu
For laboratory research use only. Not for human or veterinary use.
About hCG
Human chorionic gonadotropin (hCG) is a glycoprotein hormone naturally produced during pregnancy that acts on LH receptors to stimulate gonadal function. It is one of the most extensively studied hormones in reproductive endocrinology, with decades of published clinical data. Researchers use hCG to investigate LH-receptor-mediated processes including testosterone production, ovulation, and gonadal function maintenance.
Human chorionic gonadotropin (hCG) is a glycoprotein hormone naturally produced during pregnancy that acts on LH receptors to stimulate gonadal function. It is one of the most extensively studied hormones in reproductive endocrinology, with decades of published clinical data. Researchers use hCG to investigate LH-receptor-mediated processes including testosterone production, ovulation, and gonadal function maintenance.
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblast cells of the placenta. Its alpha subunit is identical to LH, FSH, and TSH; the beta subunit confers specificity. hCG binds to LH/CG receptors on Leydig cells in the testes, activating adenylyl cyclase/cAMP signaling, which stimulates cholesterol conversion to pregnenolone and downstream steroidogenesis (testosterone synthesis). Also supports Sertoli cell function and spermatogenesis. In women, stimulates ovulation via LH-like activity.
Mechanism clarity: Fully characterized
Tags
Key takeaways
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Research score 10/10
2847+ published studies in the dataset
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Evidence tier: Established
Established — FDA-approved, decades of clinical use. Robust human data for fertility, hypogonadism, and TRT support. One of the most studied peptides/hormones in this list.
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Human data
FDA-approved (Pregnyl, Novarel); decades of clinical use across multiple indications
Storage and handling
Lyophilised powder: Refrigerated recommended
After reconstitution: Refrigerate immediately; use within 30-60 days
Safety and limitations
Studied for: Testicular function maintenance during TRT, Post-cycle therapy, Male fertility preservation, Testosterone production stimulation, Ovulation induction
Reported onset: Testosterone response within 24-72 hours; testicular volume maintenance ongoing
Reported duration: On-cycle: 250-500iu SC every other day (continuous with TRT). PCT: 1000-2500iu EOD for 2-4 weeks. Dosing in IU, not mcg.
Community reports: Essential during TRT for fertility preservation. Current Reddit meta: 'Use hCG on-cycle, not as PCT standalone.' Key debate: optimal dose (250iu vs 500iu EOD). Some users report mood improvement and 'fuller' feeling on hCG. Main concerns: estrogen management and proper cold storage after reconstitution.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Quality and specifications
Product details
- Product code
- L-HCG-10000
- Availability
- In Stock
- Evidence tier
- Established
- Format
- Lyophilized
- Purity
- 99.5%
- Vial size
- 10,000iu
Reconstitution reference
- Bacteriostatic water
- 2 mL
- Concentration
- 5000iu/mL. Standard 250iu dose = 5 units (0.05mL). Standard 500iu dose = 10 units (0.1mL). NOTE: hCG is dosed in IU, not mcg.
- Syringe
- 29-31G insulin
Research parameters
- Standard amount
- 500 µg
- Alternative amount
- 250 µg
- Vial
- 10000 mg
- Dataset estimate
- ~6.5 weeks at 500iu 3x/week (1 vial of 10,000iu). Dosed in IU.
Lab report record
- Laboratory
- Janoshik Analytical
- Test date
- 2026-03-01
- Document
- PDF not attached
See the science
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PMID 30087849
Read study: Human chorionic gonadotropin for management of infertility in hypogonadal men (opens in a new tab)
Human chorionic gonadotropin for management of infertility in hypogonadal men
hCG maintains spermatogenesis in men on TRT and prevents azoospermia. Essential for fertility preservation during testosterone replacement.
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hCG concurrent with testosterone replacement therapy
Prevents testicular atrophy during TRT by maintaining intratesticular testosterone at levels sufficient for ongoing spermatogenesis and Leydig cell function.
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hCG in post-cycle therapy and Leydig cell restoration
Restores Leydig cell function post-AAS use with dose-dependent testosterone response. Current community meta favors on-cycle use over standalone PCT.
Studies are listed for reference. Most were carried out in animal or cell models; their findings do not establish safety or effect in humans.
Further reading
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 10-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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1 year agor/Testosterone · Post
HCG … injecting HCG SubQ … experience the benefits of HCG
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4 years agor/Testosterone · Post
hCG … symptoms faded
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8 months agor/Testosterone · Post
However at that rate I'm using my HCG (from TRT Nation) twice as fast as the rx so need to find a good HCG source. … Yeah I think I’m going to drop it to 250IU’s M-W-F, how long was it until you started feeling any improvements, I just did
Based on 5 qualifying reports from 5 threads. 26 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Questions about hCG
Questions and answers recorded for this product.
hCG is a glycoprotein hormone (not a simple peptide), and its biological activity is measured in International Units (IU) rather than by mass. This is because the biological potency can vary between preparations, so IU standardizes the actual biological effect. A standard vial contains 10,000iu. Typical TRT support dosing is 250-500iu every other day or 3x per week.
Current consensus strongly favors using hCG concurrently with TRT (on-cycle) rather than only for PCT. On-cycle use maintains testicular size, intratesticular testosterone, and spermatogenesis throughout. Using hCG only post-cycle means the testes have already atrophied and recovery takes longer. The typical on-cycle dose is 250-500iu every other day or 3x/week.
Yes. Lyophilized (powder) hCG should be stored refrigerated for best stability. After reconstitution with bacteriostatic water, it MUST be refrigerated and used within 30-60 days. hCG is a large glycoprotein hormone that is more sensitive to temperature than smaller peptides. Never freeze reconstituted hCG.
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