MOTS-c — 10mg
189.99€
Epithalon — 10mg
The only peptide shown to reactivate telomerase, the enzyme that maintains the protective caps on your chromosomes.
239.99€
Ex Tax 239.99€
- In Stock
- Evidence tier: Experimental
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
For laboratory research use only. Not for human or veterinary use.
About Epithalon
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging. Originally developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon is the most directly studied peptide in telomere biology research.
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging. Originally developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon is the most directly studied peptide in telomere biology research.
Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analog of epithalamin, the naturally occurring pineal gland peptide. It activates telomerase reverse transcriptase (hTERT) gene expression in somatic cells, leading to telomerase enzyme activation and telomere elongation. In telomerase-negative human fetal fibroblasts, epithalon induced catalytic subunit expression, enzymatic telomerase activity, and measurable telomere lengthening. Additional mechanisms include melatonin production regulation, antioxidant enzyme activation, and possible epigenetic modulation. Developed by Prof. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology.
Mechanism clarity: Well-characterized
Tags
Key takeaways
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Research score 5/10
100+ published studies in the dataset
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Evidence tier: Experimental
Experimental — Primarily in-vitro and animal data from Russian research groups (Khavinson lab). The telomerase mechanism is well-demonstrated in cell culture. Animal longevity data is promising. No Western RCTs. The science is plausible but the evidence base is narrow (largely one research group).
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Human data
In-vitro human cells; no RCTs
Storage and handling
Lyophilised powder: Room temp or refrigerated
After reconstitution: Refrigerate, use within 21 days
Safety and limitations
Studied for: Anti-aging, Telomere maintenance, Sleep quality, Cellular regeneration, Immune support
Reported onset: Sleep improvements in 3-5 days; telomere effects require months of cycling
Reported duration: 10-day on / 6-month off cycling protocol; 5-10mg SC daily during on-phase
Community reports: Users report improved sleep quality within first week (melatonin effect). Subjective vitality improvements noted. Hard to verify telomere effects without expensive testing. Short cycle protocol (10-20 days) with 4-6 month breaks is well-tolerated.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Quality and specifications
Product details
- Product code
- L-EPITH-10
- Availability
- In Stock
- Evidence tier
- Experimental
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Reconstitution reference
- Bacteriostatic water
- 1 mL
- Concentration
- 100mcg per unit (0.01mL). 5mg dose = 50 units.
- Syringe
- 29-31G insulin
Research parameters
- Standard amount
- 5000 µg
- Alternative amount
- 10000 µg
- Vial
- 10 mg
- Dataset estimate
- 1 vial lasts ~2 days at 5mg/day (10-day cycle needs 5 vials)
Lab report record
- Laboratory
- Janoshik Analytical
- Test date
- 2026-03-01
- Document
- PDF not attached
See the science
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Epithalon and pineal gland function in aging models
Restored melatonin production in aging animals; improved circadian rhythm and extended lifespan in rodent models.
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PMID 12411320
Read study: Epitalon increases telomere length through telomerase upregulation (opens in a new tab)
Epitalon increases telomere length through telomerase upregulation
Confirmed telomere lengthening in human cell lines via multiple mechanisms including hTERT activation.
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PMID 12937682
Read study: Epithalon induces telomerase activity and telomere elongation in human somatic cells (opens in a new tab)
Epithalon induces telomerase activity and telomere elongation in human somatic cells
Reactivated telomerase in telomerase-negative fibroblasts; induced measurable telomere elongation in human cell lines.
Studies are listed for reference. Most were carried out in animal or cell models; their findings do not establish safety or effect in humans.
Further reading
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 10-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
The latest successful refresh is at least 30 days old. Source data may be stale.
Selected reports
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1 year agor/insomnia · Post
Epitalon … started Epitalon … My Circadian Rhythm has fully been reseted
Based on 1 qualifying reports from 1 threads. 40 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Questions about Epithalon
Questions and answers recorded for this product.
This is a common question. While cancer cells typically have active telomerase, no published Epithalon studies have shown cancer promotion. Cancer cells already have telomerase active independently. The short cycle protocol (10-20 days) also limits exposure. However, Epithalon should not be used by anyone with active cancer.
The standard research protocol is 5-10mg SC daily for 10 consecutive days, followed by a 4-6 month off period. This cyclic approach (10 days on / 6 months off) is based on the original Khavinson laboratory protocols. It is not intended for continuous daily use.
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging.
Reviews
There are no reviews for this product yet.
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