Ipamorelin — 10mg
159.99€
Tesamorelin — 10mg
The only GHRH analog that completed Phase 3 FDA trials. 44 amino acids. One target: visceral adipose tissue. Research score: 10/10.
279.99€
Ex Tax 279.99€
- In Stock
- Evidence tier: Established
- Format: Lyophilized
- Purity: 99.4%
- Vial size: 10mg
For laboratory research use only. Not for human or veterinary use.
About Tesamorelin
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that has been studied extensively for its effects on visceral adipose tissue and body composition. It is one of the few peptides in this class with published, peer-reviewed clinical data specifically documenting changes in trunk fat. Researchers value it for its selectivity and its well-characterized safety profile.
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that has been studied extensively for its effects on visceral adipose tissue and body composition. It is one of the few peptides in this class with published, peer-reviewed clinical data specifically documenting changes in trunk fat. Researchers value it for its selectivity and its well-characterized safety profile.
Tesamorelin is a synthetic 44-amino acid analog of GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus, providing resistance to dipeptidyl peptidase-4 (DPP-4) degradation. It binds GHRH receptors on anterior pituitary somatotrophs, stimulating GH synthesis and secretion via cAMP signaling. This increases endogenous GH pulsatility while preserving the hypothalamic-pituitary feedback axis. The GH elevation drives IGF-1 production, lipolysis (particularly visceral adipose tissue), and improved body composition.
Mechanism clarity: Well-characterized
Tags
Key takeaways
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Research score 10/10
200+ published studies in the dataset
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Evidence tier: Established
Established — FDA-approved (Egrifta) with multiple Phase 3 RCTs. Robust human data for visceral fat reduction. Off-label use for anti-aging is well-supported by mechanism but less studied.
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Reality tier: Established
FDA-approved as Egrifta for HIV lipodystrophy. Phase III RCTs. Comprehensive human safety and efficacy data.
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Human data
Phase III RCTs, FDA-approved (Egrifta)
Storage and handling
Lyophilised powder: Refrigerated
After reconstitution: Use immediately after reconstitution
Safety and limitations
Studied for: Visceral fat reduction, Anti-aging / GH optimization, Body recomposition, NAFLD/fatty liver improvement, Cognitive function support
Reported onset: Visceral fat reduction noticeable within 8-12 weeks; IGF-1 elevation within 2-4 weeks
Reported duration: 3-6 months on, 1-2 months off; 1-2mg SC daily (FDA dose: 2mg/day)
Community reports: Well-respected in anti-aging and peptide communities as a 'real' peptide (FDA-approved). Users report noticeable visceral fat reduction within 8-12 weeks. Commonly compared to sermorelin and ipamorelin. Main concern: cost and daily injection requirement. Steady demand from the anti-aging crowd.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Quality and specifications
Product details
- Product code
- L-TESA-10
- Availability
- In Stock
- Evidence tier
- Established
- Format
- Lyophilized
- Purity
- 99.4%
- Vial size
- 10mg
Reconstitution reference
- Bacteriostatic water
- 2 mL
- Concentration
- 10mcg per unit. Full 2mg dose = 200 units (2mL, full syringe on 1mL or use 3mL syringe).
- Syringe
- 29-31G insulin
Research parameters
- Standard amount
- 2000 µg
- Alternative amount
- 1000 µg
- Vial
- 10 mg
- Dataset estimate
- ~5 days at 2mg/day (1 vial of 10mg). Multiple vials needed per cycle.
Lab report record
- Laboratory
- Janoshik Analytical
- Test date
- 2026-03-01
- Document
- PDF not attached
See the science
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PMID 20592130
Read study: Tesamorelin for visceral fat reduction in HIV (opens in a new tab)
Tesamorelin for visceral fat reduction in HIV
Significantly reduced trunk fat and improved lipid profiles in large-scale RCT.
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PMID 26050793
Read study: Tesamorelin and cognitive function (opens in a new tab)
Tesamorelin and cognitive function
Improved executive function and verbal memory in adults with mild cognitive impairment or subjective cognitive complaints.
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PMID 29590385
Read study: Tesamorelin effects on hepatic fat (opens in a new tab)
Tesamorelin effects on hepatic fat
Reduced liver fat and improved markers of NAFLD.
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PMID 22082200
Read study: Growth hormone and tesamorelin in the treatment of HIV-associated lipodystrophy (opens in a new tab)
Growth hormone and tesamorelin in the treatment of HIV-associated lipodystrophy
Tesamorelin significantly reduced visceral adipose tissue in HIV-associated lipodystrophy, providing the basis for FDA approval as Egrifta.
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PMID 17855669
Read study: Metabolic effects of a growth hormone-releasing factor in patients with HIV (opens in a new tab)
Metabolic effects of a growth hormone-releasing factor in patients with HIV
Significant trunk fat reduction with improved triglyceride levels in NEJM published trial (Falutz et al.). Key basis study for FDA approval.
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Tesamorelin effects on NAFLD and cognitive function in aging
Emerging data shows NAFLD fat reduction and cognitive improvement in aging populations. Tesamorelin's effects extend beyond HIV lipodystrophy to broader metabolic and neuroprotective applications.
Studies are listed for reference. Most were carried out in animal or cell models; their findings do not establish safety or effect in humans.
Further reading
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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7 months agor/Biohackers · Post
Tesamorelin … gave myself time to reset. During that cycle I experienced really good results … really good results
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8 months agor/ResearchCompounds · Post
Anybody else experience side effects from tesamorelin? Starting my 3rd month I really noticed side effects. I feel like my head is swollen. I feel dizzy and I have almost passed out a few times. I'm not diabetic, but I feel like it's how a diabetic feels? I've occasionally had
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2 years agor/Peptides · Post
I have been on Tesamorelin about 400-500mcg 6 nights on 1 night off per week and while luckily some side effects like my wrists aching and the aggression are going away, I am not sure how I should be eating to see any results. … I have been on Tesamorelin about 400-500mcg 6 nigh…
Based on 3 qualifying reports from 3 threads. 33 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Questions about Tesamorelin
Questions and answers recorded for this product.
Both are GHRH analogs, but tesamorelin is a full 44-amino acid GHRH analog with a trans-3-hexenoic acid modification for DPP-4 resistance, while sermorelin is only the first 29 amino acids. Tesamorelin is FDA-approved (Egrifta) with specific clinical data on visceral fat reduction via CT imaging. Sermorelin has broader anti-aging clinic use. Tesamorelin is considered more potent for visceral fat specifically.
Yes — tesamorelin (GHRH pathway) and ipamorelin (ghrelin/GHS pathway) stimulate GH release through two independent receptor systems. This dual-pathway approach is studied for potentially amplified GH output compared to either compound alone. This is one of the most popular GH peptide stacks for targeted visceral fat reduction.
Published clinical protocols use 2mg SC daily continuously. The research community typically runs 3-6 month cycles with 1-2 month breaks. CT imaging studies showed visceral fat reduction within 8-12 weeks, with continued improvement through 6 months. Most anti-aging practitioners recommend monitoring IGF-1 levels periodically during use.
Both are GHRH analogs. Tesamorelin is more potent, has FDA approval, and has stronger clinical data. Sermorelin has a longer track record and lower cost.
Yes. Tesamorelin is FDA-approved as Egrifta® for reduction of excess abdominal fat in HIV-associated lipodystrophy.
Tesamorelin has higher synthesis costs and is the most potent GHRH analog available with robust Phase III clinical trial data. Its pharmaceutical pedigree commands premium pricing.
Reviews
There are no reviews for this product yet.
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