BPC-157 — 5mg
109.99€
LL-37 — 10mg
The sole cathelicidin antimicrobial peptide in the human immune system, capable of forming physical pores in bacterial membranes.
139.99€
Ex Tax 139.99€
- In Stock
- Evidence tier: Experimental
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
For laboratory research use only. Not for human or veterinary use.
About LL-37
LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It is produced by immune cells, epithelial cells, and other tissues as a first-line defense against pathogens. Beyond direct antimicrobial activity, published research documents LL-37's roles in immune cell recruitment, inflammation modulation, wound healing, and biofilm disruption. It sits at the intersection of antimicrobial defense and tissue repair — two processes the body rarely separates.
LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It is produced by immune cells, epithelial cells, and other tissues as a first-line defense against pathogens. Beyond direct antimicrobial activity, published research documents LL-37's roles in immune cell recruitment, inflammation modulation, wound healing, and biofilm disruption. It sits at the intersection of antimicrobial defense and tissue repair — two processes the body rarely separates.
LL-37 is the sole human cathelicidin antimicrobial peptide, a 37-amino acid alpha-helical peptide derived from proteolytic cleavage of the 18kDa precursor hCAP-18. It operates through multiple mechanisms: direct antimicrobial action via membrane disruption (oligomerizes to form transmembrane pores in bacterial membranes), LPS/endotoxin neutralization, chemotaxis of immune cells (neutrophils, monocytes, T-cells), inhibition of neutrophil apoptosis, stimulation of angiogenesis and tissue regeneration, and modulation of cytokine release (IL-8, TNF-alpha). Its production is upregulated by vitamin D3, bacterial products, and inflammation.
Mechanism clarity: Well-characterized
Tags
Key takeaways
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Research score 6/10
200+ published studies in the dataset
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Evidence tier: Experimental
Experimental — Well-characterized as a natural immune peptide with extensive in-vitro and animal data. Clinical research ongoing for wound healing and infection. No completed human RCTs for injectable use. The mechanism is well-established but therapeutic application is early-stage.
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Reality tier: Emerging
Good mechanistic understanding. Antimicrobial + wound healing data. Limited clinical application studies.
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Human data
In-vitro human cell data
Storage and handling
Lyophilised powder: Room temp or refrigerated
After reconstitution: Refrigerate, use within 30 days
Safety and limitations
Studied for: Immune defense, Biofilm disruption, Wound healing, Chronic infections, Antimicrobial defense
Reported onset: Immune effects within days; chronic infection management over 2-4 weeks
Reported duration: 2-4 weeks; 100-200mcg SC daily
Community reports: Niche peptide used mainly in chronic illness communities (Lyme, long COVID, CFS). Positive reports for chronic infection management. Key concern: LL-37 overexpression is implicated in psoriasis and lupus, so use should be time-limited. Contraindicated in active autoimmune conditions. Low doses recommended — this is potent.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Quality and specifications
Product details
- Product code
- L-LL37-10
- Availability
- In Stock
- Evidence tier
- Experimental
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Reconstitution reference
- Bacteriostatic water
- 2 mL
- Concentration
- 25mcg per unit. 100mcg dose = 4 units.
- Syringe
- 29-31G insulin
Research parameters
- Standard amount
- 200 µg
- Alternative amount
- 100 µg
- Vial
- 10 mg
- Dataset estimate
- 1 vial lasts ~7 weeks at 200mcg/day
Lab report record
- Laboratory
- Janoshik Analytical
- Test date
- 2026-03-01
- Document
- PDF not attached
See the science
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PMID 16352721
Read study: LL-37, the only human member of the cathelicidin family (opens in a new tab)
LL-37, the only human member of the cathelicidin family
Comprehensive review of LL-37's antimicrobial, immunomodulatory, and wound healing properties.
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PMID 18036595
Read study: Cathelicidin antimicrobial peptide in wound healing (opens in a new tab)
Cathelicidin antimicrobial peptide in wound healing
LL-37 promotes wound vascularization and re-epithelialization.
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PMID 20049649
Read study: Cathelicidin LL-37: a multitask antimicrobial peptide (opens in a new tab)
Cathelicidin LL-37: a multitask antimicrobial peptide
LL-37 is antimicrobial, chemoattractant, anti-apoptotic, and angiogenic; production is regulated by vitamin D3.
Studies are listed for reference. Most were carried out in animal or cell models; their findings do not establish safety or effect in humans.
Further reading
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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1 year agor/badbreath · Post
LL-37 … what worked for me is LL-37 … I might have actually beaten chronic bad breath
Based on 1 qualifying reports from 1 threads. 12 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Questions about LL-37
Questions and answers recorded for this product.
LL-37 interferes with bacterial quorum sensing (communication) and destabilizes the extracellular matrix that protects biofilm communities. Published research shows LL-37 can penetrate and disrupt established biofilms at concentrations where conventional antibiotics fail.
LL-37 has direct antimicrobial activity (kills bacteria) in addition to immune signaling, unlike purely signaling peptides like Thymosin Alpha-1.
The only cathelicidin antimicrobial peptide produced by the human body. It serves as part of the innate immune defense system.
Reviews
There are no reviews for this product yet.
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