Sermorelin Acetate — 10mg
234.99€
Ipamorelin — 10mg
A growth hormone peptide so selective that researchers couldn't break its specificity at 200x the dose.
159.99€
Ex Tax 159.99€
- In Stock
- Evidence tier: Emerging
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
For laboratory research use only. Not for human or veterinary use.
About Ipamorelin
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a pentapeptide (Aib-His-D-2Nal-D-Phe-Lys-NH2) growth hormone secretagogue that selectively activates ghrelin/GHS-R1a receptors on anterior pituitary somatotrophs. What makes it unique among GHRPs is its remarkable selectivity: it stimulates GH release with potency comparable to GHRP-6 but does not stimulate ACTH, cortisol, prolactin, or aldosterone secretion, even at doses 200-fold above the ED50 for GH release. This selectivity mirrors GHRH rather than other GHRP-receptor agonists. It also shows moderate resistance to metabolism with ~60-80% recovered intact.
Mechanism clarity: Well-characterized
Tags
Key takeaways
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Research score 7/10
78+ published studies in the dataset
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Evidence tier: Emerging
Emerging — Some human clinical data (post-surgical applications), extensive pharmacological characterization. The selectivity profile is well-established in clinical pharmacology studies. Less clinical trial data than sermorelin or tesamorelin for anti-aging applications.
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Human data
Phase I/II human data (post-surgical GI recovery); extensive pharmacological characterization in humans
Storage and handling
Lyophilised powder: Room temperature or refrigerated
After reconstitution: Refrigerate; use within 30 days
Safety and limitations
Studied for: Growth hormone optimization, Sleep quality improvement, Fat loss and body recomposition, Recovery from training, Anti-aging protocols
Reported onset: Sleep improvement within 1-2 weeks; body composition changes over 8-12 weeks
Reported duration: 8-16 weeks on, 4 weeks off; 200-300mcg SC 2-3x daily
Community reports: Very clean profile — no hunger spikes (unlike GHRP-6), no cortisol elevation. Users report improved sleep quality first, then gradual body composition improvements. Most commonly stacked with CJC-1295 (no DAC) for the 'gold standard' GH peptide stack.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Quality and specifications
Product details
- Product code
- L-IPAM-10
- Availability
- In Stock
- Evidence tier
- Emerging
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Reconstitution reference
- Bacteriostatic water
- 2 mL
- Concentration
- 5mg/mL (5mcg per unit). Standard 200mcg dose = 40 units (0.04mL).
- Syringe
- 29-31G insulin
Research parameters
- Standard amount
- 200 µg
- Alternative amount
- 300 µg
- Vial
- 10 mg
- Dataset estimate
- ~3.5 weeks at 200mcg 2x/day (1 vial of 10mg)
Lab report record
- Laboratory
- Janoshik Analytical
- Test date
- 2026-03-01
- Document
- PDF not attached
See the science
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PMID 9849822
Read study: Ipamorelin, the first selective growth hormone secretagogue (opens in a new tab)
Ipamorelin, the first selective growth hormone secretagogue
First GHRP with selectivity for GH similar to GHRH; no ACTH/cortisol increase even at 200x the ED50 for GH release.
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PMID 9849822
Read study: Pharmacological characterization of ipamorelin (opens in a new tab)
Pharmacological characterization of ipamorelin
5-fold lower systemic clearance than GHRP-6; 60-80% recovered intact. Clean, dose-dependent GH release without desensitization.
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Ipamorelin in post-surgical GI recovery
Improved bowel function post-surgery in human clinical studies. One of the few GH secretagogues with human clinical trial data.
Studies are listed for reference. Most were carried out in animal or cell models; their findings do not establish safety or effect in humans.
Further reading
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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11 months agor/BodyHackGuide · Post
Ipamorelin … Tesamorelin + Ipamorelin … my recovery improved, sleep got deeper, and the stubborn visceral fat around my midsection finally started moving
Based on 1 qualifying reports from 1 threads. 21 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Questions about Ipamorelin
Questions and answers recorded for this product.
Ipamorelin is the most selective GH secretagogue identified. Unlike GHRP-6 (which causes intense hunger) or GHRP-2 (which elevates cortisol and prolactin), ipamorelin stimulates growth hormone release without significantly affecting cortisol, prolactin, ACTH, or aldosterone — even at doses 200x above the effective dose. This selectivity makes it the cleanest option for GH research.
Yes — ipamorelin (ghrelin receptor pathway) and sermorelin or CJC-1295 (GHRH receptor pathway) work through two completely different receptor systems on the pituitary. Published research suggests dual-pathway stimulation produces greater GH release than either alone. The ipamorelin + CJC-1295 (no DAC) combination is one of the most studied GH peptide stacks in the research community.
Most research protocols administer ipamorelin before bed on an empty stomach (2-3 hours post-meal) to amplify the natural nocturnal GH pulse. Some protocols include a second dose upon waking, also fasted. GH release is blunted by food intake (particularly carbohydrates and fats), so timing around meals matters for optimal pulsatile response.
Reviews
There are no reviews for this product yet.
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