BPC-157 — 5mg
109.99€
The dual GIP/GLP-1 agonist that outperformed semaglutide in every head-to-head clinical trial.
329.99€
Prijs per flacon · Excl. btw 329.99€
Uitsluitend voor laboratoriumonderzoek. Niet voor gebruik bij mens of dier.
Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist that has become one of the most studied peptides in modern metabolic research. It simultaneously targets two incretin pathways, making it a subject of intense scientific interest for its role in glucose metabolism and body composition. Researchers continue to investigate its unique dual mechanism, which distinguishes it from single-agonist compounds.
Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist that has become one of the most studied peptides in modern metabolic research. It simultaneously targets two incretin pathways, making it a subject of intense scientific interest for its role in glucose metabolism and body composition. Researchers continue to investigate its unique dual mechanism, which distinguishes it from single-agonist compounds.
Tirzepatide is a 39-amino acid acylated peptide with a C20 fatty diacid moiety enabling once-weekly dosing. It acts as an imbalanced dual agonist: full potency at the GIP receptor (equal affinity to native GIP) and approximately 5-fold weaker affinity at the GLP-1 receptor vs native GLP-1. This imbalanced pharmacology drives unique signaling bias. Activates cAMP accumulation through both GIPR and GLP-1R, enhancing glucose-dependent insulin secretion, suppressing glucagon, delaying gastric emptying, and reducing food intake via central appetite circuits.
Duidelijkheid van het mechanisme: Well-characterized
5,000+ gepubliceerde studies in de dataset
Established — Robust Phase 3 data (SURPASS 1-5, SURMOUNT 1-4), FDA-approved as Mounjaro (T2D) and Zepbound (obesity). Thousands of participants across RCTs.
Large RCTs (thousands of participants)
Gevriesdroogd poeder: Room temp or refrigerated
Na reconstitutie: Refrigerate, use within 30 days
Onderzocht voor: Weight loss, Type 2 diabetes, Metabolic syndrome, Appetite suppression, Body recomposition
Gemelde aanvang: 1-2 weeks for appetite suppression; 4-8 weeks for significant weight loss
Gemelde duur: Ongoing; dose escalation over 4-week intervals from 2.5mg to 15mg
Meldingen uit de community: Nausea common in first 2-4 weeks at each dose escalation, usually subsides. Most users report 1-2 lbs/week loss. Weight regain documented in 82% upon cessation.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
The Role of Tirzepatide in Management of T2D: SURPASS Trials
39-amino acid synthetic peptide; dose-dependent weight loss up to 12.4%
Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for T2D
First dual agonist approved; superior HbA1c and weight reduction vs semaglutide
Tirzepatide for obesity in adults without diabetes
Up to 22.5% body weight loss at 15mg dose over 72 weeks
Studies worden ter referentie vermeld. De meeste zijn uitgevoerd in dier- of celmodellen; de resultaten tonen geen veiligheid of werking bij mensen aan.
I started tirzepatide this past Friday at 2.0 mg. … Immediately, I was already feeling the effects, specifically with the appetite suppression.
Hey everyone, I'm about 4 months into my tirzepatide journey and wanted to share what I've learned. I'm 42, started at 240, and I'm down 45 pounds as of this week. This stuff works, but there's a lot they don't tell you. First, the good stuff: The weight loss is real. I'm
About two months ago, I started tirzepatide at a very low dose (2.5 mg) for reasons unrelated to PMDD. … I’m not exaggerating when I say I’ve had a ~95% improvement in quality of life.
Based on 4 qualifying reports from 4 threads. 37 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Vragen en antwoorden die bij dit product zijn vastgelegd.
Clinical data shows weight regain in approximately 82% of participants after discontinuation. Most researchers view it as an ongoing protocol rather than a short cycle.
Tirzepatide is the active compound. Mounjaro is the brand name for type 2 diabetes, Zepbound for obesity. Research-grade tirzepatide is the same molecule.
Tirzepatide is a dual agonist (GIP + GLP-1) while semaglutide targets only GLP-1. Clinical trials show tirzepatide produces roughly 50% more weight loss. It also tends to have a different side effect profile.
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