MOTS-c — 10mg
189.99€
Epithalon — 10mg
The only peptide shown to reactivate telomerase, the enzyme that maintains the protective caps on your chromosomes.
239.99€
Excl. btw 239.99€
- In Stock
- Evidence tier: Experimental
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
Uitsluitend voor laboratoriumonderzoek. Niet voor gebruik bij mens of dier.
Over Epithalon
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging. Originally developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon is the most directly studied peptide in telomere biology research.
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging. Originally developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, Epithalon is the most directly studied peptide in telomere biology research.
Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analog of epithalamin, the naturally occurring pineal gland peptide. It activates telomerase reverse transcriptase (hTERT) gene expression in somatic cells, leading to telomerase enzyme activation and telomere elongation. In telomerase-negative human fetal fibroblasts, epithalon induced catalytic subunit expression, enzymatic telomerase activity, and measurable telomere lengthening. Additional mechanisms include melatonin production regulation, antioxidant enzyme activation, and possible epigenetic modulation. Developed by Prof. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology.
Duidelijkheid van het mechanisme: Well-characterized
Tags
Belangrijkste punten
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Onderzoeksscore 5/10
100+ gepubliceerde studies in de dataset
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Bewijsniveau: Experimental
Experimental — Primarily in-vitro and animal data from Russian research groups (Khavinson lab). The telomerase mechanism is well-demonstrated in cell culture. Animal longevity data is promising. No Western RCTs. The science is plausible but the evidence base is narrow (largely one research group).
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Gegevens bij mensen
In-vitro human cells; no RCTs
Opslag en hantering
Gevriesdroogd poeder: Room temp or refrigerated
Na reconstitutie: Refrigerate, use within 21 days
Veiligheid en beperkingen
Onderzocht voor: Anti-aging, Telomere maintenance, Sleep quality, Cellular regeneration, Immune support
Gemelde aanvang: Sleep improvements in 3-5 days; telomere effects require months of cycling
Gemelde duur: 10-day on / 6-month off cycling protocol; 5-10mg SC daily during on-phase
Meldingen uit de community: Users report improved sleep quality within first week (melatonin effect). Subjective vitality improvements noted. Hard to verify telomere effects without expensive testing. Short cycle protocol (10-20 days) with 4-6 month breaks is well-tolerated.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Kwaliteit en specificaties
Product details
- Productcode
- L-EPITH-10
- Beschikbaarheid
- In Stock
- Evidence tier
- Experimental
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Reconstitutiereferentie
- Bacteriostatisch water
- 1 mL
- Concentratie
- 100mcg per unit (0.01mL). 5mg dose = 50 units.
- Spuit
- 29-31G insulin
Onderzoeksparameters
- Standaardhoeveelheid
- 5000 µg
- Alternatieve hoeveelheid
- 10000 µg
- Flacon
- 10 mg
- Schatting uit de dataset
- 1 vial lasts ~2 days at 5mg/day (10-day cycle needs 5 vials)
Laboratoriumrapport
- Laboratorium
- Janoshik Analytical
- Testdatum
- 2026-03-01
- Document
- Pdf niet bijgevoegd
Bekijk de wetenschap
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Epithalon and pineal gland function in aging models
Restored melatonin production in aging animals; improved circadian rhythm and extended lifespan in rodent models.
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PMID 12411320
Lees de studie: Epitalon increases telomere length through telomerase upregulation (opent in een nieuw tabblad)
Epitalon increases telomere length through telomerase upregulation
Confirmed telomere lengthening in human cell lines via multiple mechanisms including hTERT activation.
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PMID 12937682
Lees de studie: Epithalon induces telomerase activity and telomere elongation in human somatic cells (opent in een nieuw tabblad)
Epithalon induces telomerase activity and telomere elongation in human somatic cells
Reactivated telomerase in telomerase-negative fibroblasts; induced measurable telomere elongation in human cell lines.
Studies worden ter referentie vermeld. De meeste zijn uitgevoerd in dier- of celmodellen; de resultaten tonen geen veiligheid of werking bij mensen aan.
Verder lezen
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 10-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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1 year agor/insomnia · Post
Epitalon … started Epitalon … My Circadian Rhythm has fully been reseted
Based on 1 qualifying reports from 1 threads. 40 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Vragen over Epithalon
Vragen en antwoorden die bij dit product zijn vastgelegd.
This is a common question. While cancer cells typically have active telomerase, no published Epithalon studies have shown cancer promotion. Cancer cells already have telomerase active independently. The short cycle protocol (10-20 days) also limits exposure. However, Epithalon should not be used by anyone with active cancer.
The standard research protocol is 5-10mg SC daily for 10 consecutive days, followed by a 4-6 month off period. This cyclic approach (10 days on / 6 months off) is based on the original Khavinson laboratory protocols. It is not intended for continuous daily use.
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for its ability to activate telomerase — the enzyme that maintains telomere length, one of the most fundamental biomarkers of biological aging.
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PeptidesEuro is a research materials supplier operated by Pepticore LLC. We provide high-purity peptides and research compounds for in-vitro laboratory and scientific research purposes. All products are sold strictly for research use only and are not intended for human or animal consumption.
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