Beginner · 3-6 months

Sermorelin Nightly GH Protocol

The classic bedtime GH-releasing hormone: 300mcg SC nightly. One of the best-studied GH peptides — formerly FDA-approved as Geref. Long cycles (3-6 months) for maximum anti-aging benefit.

Type: single
Source: evidence-based
Pattern: 3-6 months on, 1-2 months off

Compounds

Sermorelin
SC · Before bedtime (aligns with natural GH surge during sleep). Empty stomach preferred.

300 mcg
daily

Notes

Supply: 300mcg/day = 9mg/month. Very short half-life (~10-20 min) but triggers sustained GH release. Sleep improvement in 2-4 weeks; body composition changes 2-3 months. Full anti-aging effects 3-6 months.

Source notes

FDA-approved diagnostic agent (Geref). RxList: 0.2-0.3mg SC at bedtime. PMID: 9519944. Olympia Pharmacy: 300mcg nightly. Defy Medical: 500mcg. Empower Pharmacy: 0.2-0.3mg at bedtime.

For research and educational use only. This content is not medical advice.