Thymalin
Thymalin is a polypeptide complex originally extracted from calf thymus gland, now produced synthetically. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Biogerontology, it has been studied for over 30 years in Russian longevity research. Thymalin is the foundational Khavinson peptide, studied for thymic function restoration and immune system modulation in aging.
- Research score
- 5/10
- Reality tier
- experimental
Mechanism
Thymalin modulates T-cell maturation and differentiation, restores age-related thymic involution, and regulates cytokine expression. Long-term studies suggest effects on neuroendocrine-immune interactions.
Evidence note
30+ years Khavinson research. One notable longevity cohort study (reduced mortality). Limited Western replication.
Studies
Khavinson peptides and longevity
Long-term administration of thymic and pineal peptides associated with reduced mortality in elderly cohort study.
Open source · PMID 12577685Khavinson peptides and aging
Review of bioregulatory peptides showing effects on gene expression and age-related functional decline.
Open source · PMID 21261521
FAQ
How does Thymalin relate to the thymus?
The thymus gland shrinks with age (thymic involution), weakening immune function. Thymalin is studied for its potential to modulate thymic function and T-cell maturation in aging.
What are Khavinson peptides?
A class of bioregulatory peptides developed by Professor Vladimir Khavinson, studied for 30+ years at the St. Petersburg Institute of Biogerontology for anti-aging and organ-specific restoration effects.
For research and educational use only. This content is not medical advice.