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Experimental

Pinealon

Pinealon (Glu-Asp-Arg) is a tripeptide bioregulator developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Biogerontology. Research focuses on its effects on pineal gland function, melatonin regulation, and circadian rhythm modulation. It belongs to the Khavinson class of bioregulatory peptides studied for decades in Russian gerontology.

Aliases: Glu-Asp-Arg

Research score
4/10
Reality tier
experimental

Mechanism

Pinealon penetrates cell membranes and interacts with DNA, potentially regulating gene expression related to pineal gland function and melatonin synthesis. It is hypothesized to restore age-related decline in pineal activity.

Evidence note

Khavinson bioregulatory peptide. Gene expression data from Russian research. Limited Western validation.

Studies

  • Short peptides and gene regulation

    Demonstrated that short bioregulatory peptides like Pinealon can penetrate cell nuclei and interact with DNA.

    Open source · PMID 18454303
  • Khavinson peptides and aging

    Review of bioregulatory peptides showing effects on gene expression and age-related functional decline.

    Open source · PMID 21261521

FAQ

How does Pinealon relate to melatonin?

Pinealon is studied for its effects on pineal gland function — the gland that produces melatonin. It doesn't contain melatonin but may support endogenous melatonin regulation.

What are Khavinson peptides?

A class of short bioregulatory peptides developed by Professor Vladimir Khavinson, studied for decades in Russian longevity and gerontology research.

For research and educational use only. This content is not medical advice.