NAD+ — 500mg
249.99€
Semax Spray — 30mg
The nootropic peptide with decades of clinical research across cognitive performance, neuroprotection, and BDNF upregulation.
179.99€
Excl. btw 179.99€
- In Stock
- Evidence tier: Emerging
- Format: Nasal Spray
- Purity: 99.3%
- Vial size: 30mg
Uitsluitend voor laboratoriumonderzoek. Niet voor gebruik bij mens of dier.
Over Semax Spray
Semax is a synthetic heptapeptide based on the ACTH(4-10) fragment, originally developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It has been approved in Russia as a nootropic since the 1990s and is now widely studied internationally for its effects on BDNF expression, cognitive function, and neuroprotection.
Synthetic heptapeptide based on the ACTH(4-10) fragment. Approved in Russia as a nootropic since the 1990s. Studied for BDNF expression, cognitive function, and neuroprotection.
Heptapeptide analog of ACTH(4-7) with C-terminal Pro-Gly-Pro extension. Increases BDNF protein levels (1.4-fold) and trkB tyrosine phosphorylation (1.6-fold), upregulates BDNF mRNA (3-fold) and trkB mRNA (2-fold) in hippocampus, modulates serotonergic and dopaminergic neurotransmission, activates MAPK/ERK signaling cascades.
Duidelijkheid van het mechanisme: Well-characterized (BDNF upregulation, trkB phosphorylation, MAPK/ERK signaling)
Tags
Belangrijkste punten
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Onderzoeksscore 7/10
300+ gepubliceerde studies in de dataset
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Bewijsniveau: Emerging
Approved in Russia since 1990s. Multiple animal and human studies on BDNF, cognitive function, and neuroprotection.
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Realiteitsniveau: Established
Approved prescription medication in Russia. Clinical data for stroke recovery and cognition. Not FDA-approved in US.
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Gegevens bij mensen
Russian clinical trials and prescription use data; limited Western RCTs
Opslag en hantering
Gevriesdroogd poeder: Room temp or refrigerated
Na reconstitutie: Refrigerate at 2-8°C, use within 14-21 days
Reconstitutiestappen uit de dataset
- Prepare. If using pre-made nasal spray, skip to step 5. For powder reconstitution: clean vial top with alcohol.
- Add saline. Draw 2mL bacteriostatic saline (NOT water) and inject slowly into vial.
- Dissolve. Gently swirl until fully dissolved. Solution should be clear.
- Transfer. Transfer solution to a sterile nasal spray bottle using a syringe. Each spray ≈ 0.1mL (200mcg at 5mg/mL).
- Administer. Tilt head back slightly. Insert nozzle into nostril and spray once. Alternate nostrils. Standard dose: 1-3 sprays (200-600mcg) 2-3x daily.
- Store. Refrigerate nasal spray. Use within 14-21 days after reconstitution.
Veiligheid en beperkingen
Onderzocht voor: Cognitive enhancement, Stroke recovery, BDNF modulation, Neuroprotection, ADHD symptom management
Gemelde aanvang: 5-15 minutes intranasal; 15-30 minutes subcutaneous
Gemelde duur: 2-4 week cycles on, 2 weeks off (Russian clinical protocol: 10-20 days)
Meldingen uit de community: Polarizing. Responders describe "clean stimulant without jitters" — improved focus, verbal fluency, and working memory. Non-responders notice nothing. Some report increased irritability at higher doses. Quality varies significantly between vendors. N-Acetyl Semax Amidate considered most potent form.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Kwaliteit en specificaties
Product details
- Productcode
- NS-SEMAX-30
- Beschikbaarheid
- In Stock
- Evidence tier
- Emerging
- Format
- Nasal Spray
- Purity
- 99.3%
- Vial size
- 30mg
Reconstitutiereferentie
- Bacteriostatisch water
- 2 mL
- Concentratie
- Nasal spray: ~200mcg per spray. If reconstituting from powder: 5mg/mL with 2mL bacteriostatic saline.
- Spuit
- Nasal spray bottle (not syringe)
Onderzoeksparameters
- Standaardhoeveelheid
- 600 µg
- Alternatieve hoeveelheid
- 200 µg
- Flacon
- 10 mg
- Schatting uit de dataset
- ~6 days at 600mcg 3x/day (1 vial of 10mg)
Laboratoriumrapport
Semax 10mg — Certificate of Analysis
- Laboratorium
- Janein Labs
- Testdatum
- 2026-03-01
- Status
- Passed
- Geregistreerde zuiverheid
- 99.2%
- Endotoxine
- <0.5 EU/mg
- Document
- Pdf niet bijgevoegd
Bekijk de wetenschap
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PMID 16996037
Lees de studie: Semax neuroprotective effects in ischemia (opent in een nieuw tabblad)
Semax neuroprotective effects in ischemia
Demonstrated neuroprotection and improved cognitive outcomes post-ischemic injury.
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PMID 17186529
Lees de studie: Semax and BDNF expression (opent in een nieuw tabblad)
Semax and BDNF expression
Significantly increased BDNF mRNA expression in rat hippocampus and cortex.
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PMID 22036090
Lees de studie: Semax prevents learning and memory impairment caused by transient cerebral ischemia (opent in een nieuw tabblad)
Semax prevents learning and memory impairment caused by transient cerebral ischemia
Semax administration prevented spatial learning and memory impairment in rats following cerebral ischemia, supporting neuroprotective applications.
Studies worden ter referentie vermeld. De meeste zijn uitgevoerd in dier- of celmodellen; de resultaten tonen geen veiligheid of werking bij mensen aan.
Verder lezen
Protocollen
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 10-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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2 years agor/smallfiberneuropathy · Post
Semax … try a nootropic nasal spray called Semax … profound itching precisely on the area which causes the most pain
Based on 1 qualifying reports from 1 threads. 28 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Vragen over Semax Spray
Vragen en antwoorden die bij dit product zijn vastgelegd.
Intranasal is the standard route used in Russian clinical practice and most research protocols. It provides rapid onset (5-15 minutes) and bypasses first-pass metabolism. Subcutaneous injection is less common but used by some researchers. The nasal spray format is preferred for convenience and established dosing protocols.
No. Semax is supplied as a ready-to-use nasal spray — no reconstitution or injections required.
Semax is an approved prescription medication in Russia for stroke recovery and cognitive disorders. It is sold for research purposes in the US.
Beoordelingen
Er zijn nog geen beoordelingen voor dit product.
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PeptidesEuro is a research materials supplier operated by Pepticore LLC. We provide high-purity peptides and research compounds for in-vitro laboratory and scientific research purposes. All products are sold strictly for research use only and are not intended for human or animal consumption.
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