MOTS-c — 10mg
189.99€
SS-31 — 50mg
A tetrapeptide that concentrates over 1,000-fold inside mitochondria by binding cardiolipin, the lipid that holds the inner membrane's energy-producing machinery together.
599.99€
Cena za fiolkę · Netto 599.99€
- In Stock
- Evidence tier: Emerging
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 50mg
Wyłącznie do badań laboratoryjnych. Nie do stosowania u ludzi ani zwierząt.
O produkcie SS-31
SS-31 (elamipretide) is a synthetic tetrapeptide that selectively concentrates in the inner mitochondrial membrane, where it interacts with cardiolipin — a phospholipid essential for electron transport chain function. It is the most advanced mitochondrial-targeted peptide in clinical development, with published data from multiple Phase 2 and Phase 3 trials. Researchers study SS-31 because it addresses mitochondrial dysfunction at the structural level, not just the signaling level.
SS-31 (elamipretide) is a synthetic tetrapeptide that selectively concentrates in the inner mitochondrial membrane, where it interacts with cardiolipin — a phospholipid essential for electron transport chain function. It is the most advanced mitochondrial-targeted peptide in clinical development, with published data from multiple Phase 2 and Phase 3 trials. Researchers study SS-31 because it addresses mitochondrial dysfunction at the structural level, not just the signaling level.
SS-31 (D-Arg-Dmt-Lys-Phe-NH2, also known as elamipretide/MTP-131/Bendavia) is a synthetic tetrapeptide that concentrates >1,000-fold in mitochondria due to electrostatic attraction between its positively charged arginine/lysine residues and negatively charged cardiolipin in the inner mitochondrial membrane (IMM). It stabilizes cardiolipin-dependent cristae structure, enhances electron transport chain (ETC) efficiency (particularly Complex III and IV), improves cytochrome c electron-carrying activity while reducing its peroxidase activity, scavenges reactive oxygen species, increases ATP production, and inhibits mitochondrial permeability transition pore (mPTP) opening. This prevents calcium overload and cytochrome c release (anti-apoptotic).
Poznanie mechanizmu: Well-characterized
Tagi
Najważniejsze informacje
-
Ocena badań 8/10
300+ opublikowanych badań w zbiorze danych
-
Poziom dowodów: Emerging
Emerging — Active clinical trials (Barth syndrome Phase 2/3, heart failure, kidney disease). Published in top journals (PNAS, Nature, eLife). Mechanism is well-characterized. Not yet FDA-approved but multiple clinical programs running. More human data than most peptides on this list (excluding approved ones).
-
Dane u ludzi
Phase 2/3 clinical trials
Przechowywanie i obchodzenie się
Proszek liofilizowany: Room temp or refrigerated
Po rekonstytucji: Refrigerate, use within 28 days
Bezpieczeństwo i ograniczenia
Badany w kontekście: Mitochondrial function, Anti-aging, Energy restoration, Cardiac support, Neuroprotection
Zgłaszany początek działania: Initial fatigue common in first 1-2 weeks (resolves); energy improvements by weeks 3-4
Zgłaszany czas trwania: 4-8 weeks; 2-5mg SC daily, 5 days on/2 off
Relacje społeczności: Initial fatigue/malaise is the most-discussed side effect — community recommends methyl donor supplementation (B12, betaine, glycine). After the adaptation period, users report significant energy improvements. Commonly paired with MOTS-c and NAD+. One user on r/BodyHackGuide called high-dose SS-31 + Epithalon 'best decision I ever made.'
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Jakość i specyfikacja
Product details
- Kod produktu
- L-SS31-50
- Dostępność
- In Stock
- Evidence tier
- Emerging
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 50mg
Dane do rekonstytucji
- Woda bakteriostatyczna
- 2 mL
- Stężenie
- 50mcg per unit (0.01mL). 2mg dose = 40 units.
- Strzykawka
- 29-31G insulin
Parametry badawcze
- Ilość standardowa
- 2000 µg
- Ilość alternatywna
- 5000 µg
- Fiolka
- 10 mg
- Szacunek ze zbioru danych
- 1 vial lasts ~1 week at 2mg/day (5 on/2 off)
Raport laboratoryjny
- Laboratorium
- Janoshik Analytical
- Data badania
- 2026-03-01
- Dokument
- PDF nie jest dołączony
Zobacz badania
-
PMID 19064528
Czytaj badanie: SS-31 and mitochondrial dysfunction (otwiera się w nowej karcie)
SS-31 and mitochondrial dysfunction
Restored mitochondrial function and reduced oxidative stress in aged cardiac tissue.
-
PMID 26675167
Czytaj badanie: Elamipretide in heart failure (otwiera się w nowej karcie)
Elamipretide in heart failure
Improved cardiac function in heart failure patients in Phase II clinical trials.
-
PMID 32817602
Czytaj badanie: Mitochondrial protein interaction landscape of SS-31 (PNAS) (otwiera się w nowej karcie)
Mitochondrial protein interaction landscape of SS-31 (PNAS)
SS-31 primarily interacts with cardiolipin in the inner mitochondrial membrane; comprehensive interaction map reveals direct ETC stabilization.
Badania podano w celach informacyjnych. Większość przeprowadzono na modelach zwierzęcych lub komórkowych; ich wyniki nie dowodzą bezpieczeństwa ani działania u ludzi.
Dalsza lektura
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
-
11 months agor/cfs · Post
I began to feel dizzy, woozy, and a bit lightheaded or floaty within 3-4 hours of injecting
-
1 year agor/cfs · Post
over the day, I actually lost energy
-
1 year agor/cfs · Post
I experienced nightmares, and woke up the next day with muscular PEM
Based on 3 qualifying reports from 3 threads. 25 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Pytania o SS-31
Pytania i odpowiedzi zapisane dla tego produktu.
The initial fatigue/malaise effect is well-documented in the community and typically lasts 1-2 weeks before resolving. It may relate to mitochondrial remodeling as dysfunctional mitochondria are cleared. Community recommends methyl donor supplementation (B12, betaine, glycine) and starting at lower doses (2mg/day).
Both target mitochondria but through different mechanisms. SS-31 stabilizes the electron transport chain directly, while MOTS-c activates AMPK and metabolic pathways.
Yes. As elamipretide, it is in clinical trials for Barth syndrome and other mitochondrial diseases. It has FDA Rare Pediatric Disease and Breakthrough Therapy designations.
Opinie
Ten produkt nie ma jeszcze opinii.
Powiązane produkty
-
-
NAD+ — 500mg
249.99€
-
GHK-Cu — 100mg
199.99€
-
Epithalon — 10mg
239.99€
-
SS-31 — 10mg
199.99€
Jak działa zamawianie
Dane produktu, źródła i zamówienie pozostają ze sobą powiązane.
-
Wybierz związek
Wybierz związek i rozmiar fiolki w katalogu.
-
Sprawdź informacje o produkcie
Otwórz szczegóły produktu i powiązane badania.
-
Zachowaj źródła
Zapisz źródła do swojej dokumentacji.
Dlaczego zamawiać w PeptidesEuro
Profile związków
Struktura, dostępne rozmiary i uwagi dotyczące obchodzenia się w jednym miejscu.
Źródła badań
Strony produktów prowadzą do badań dotyczących każdego związku.
Jedna historia zamówień
Zamówienia i ich szczegóły pozostają na Twoim koncie.
Przejrzyste dane produktu
Cena, dostępność i podatek przy każdym produkcie.
PeptidesEuro is a research materials supplier operated by Pepticore LLC. We provide high-purity peptides and research compounds for in-vitro laboratory and scientific research purposes. All products are sold strictly for research use only and are not intended for human or animal consumption.
No. All products sold through meimx.com are intended strictly for in-vitro laboratory and scientific research purposes only. They are not intended for human or animal consumption, injection, ingestion, inhalation, or any form of administration to living organisms. By purchasing from PeptidesEuro, you acknowledge and agree to these terms as outlined in our Terms of Service.
No. Our products have not been evaluated, approved, or authorized by the U.S. Food and Drug Administration (FDA) or any other regulatory body. They are not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. PeptidesEuro is not a compounding pharmacy or outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act.
No. PeptidesEuro does not provide medical advice, treatment recommendations, or dosing instructions. Any information on our website, including product descriptions and referenced research, is provided for educational and informational purposes only. If you have medical questions, please consult a licensed healthcare provider.
Research Use Only means that our products are sold exclusively as reference standards and research materials for use in laboratory and scientific research settings. Purchasers agree to use all products solely for legitimate research purposes in compliance with all applicable laws and regulations.
Gotowy, by zamówić SS-31?
Przeglądaj katalog albo odpowiedz na jedno pytanie w wyszukiwarce produktów.