Ipamorelin — 10mg
159.99€
The only GHRH analog that completed Phase 3 FDA trials. 44 amino acids. One target: visceral adipose tissue. Research score: 10/10.
279.99€
Excl. btw 279.99€
Uitsluitend voor laboratoriumonderzoek. Niet voor gebruik bij mens of dier.
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that has been studied extensively for its effects on visceral adipose tissue and body composition. It is one of the few peptides in this class with published, peer-reviewed clinical data specifically documenting changes in trunk fat. Researchers value it for its selectivity and its well-characterized safety profile.
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that has been studied extensively for its effects on visceral adipose tissue and body composition. It is one of the few peptides in this class with published, peer-reviewed clinical data specifically documenting changes in trunk fat. Researchers value it for its selectivity and its well-characterized safety profile.
Tesamorelin is a synthetic 44-amino acid analog of GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus, providing resistance to dipeptidyl peptidase-4 (DPP-4) degradation. It binds GHRH receptors on anterior pituitary somatotrophs, stimulating GH synthesis and secretion via cAMP signaling. This increases endogenous GH pulsatility while preserving the hypothalamic-pituitary feedback axis. The GH elevation drives IGF-1 production, lipolysis (particularly visceral adipose tissue), and improved body composition.
Duidelijkheid van het mechanisme: Well-characterized
200+ gepubliceerde studies in de dataset
Established — FDA-approved (Egrifta) with multiple Phase 3 RCTs. Robust human data for visceral fat reduction. Off-label use for anti-aging is well-supported by mechanism but less studied.
FDA-approved as Egrifta for HIV lipodystrophy. Phase III RCTs. Comprehensive human safety and efficacy data.
Phase III RCTs, FDA-approved (Egrifta)
Gevriesdroogd poeder: Refrigerated
Na reconstitutie: Use immediately after reconstitution
Onderzocht voor: Visceral fat reduction, Anti-aging / GH optimization, Body recomposition, NAFLD/fatty liver improvement, Cognitive function support
Gemelde aanvang: Visceral fat reduction noticeable within 8-12 weeks; IGF-1 elevation within 2-4 weeks
Gemelde duur: 3-6 months on, 1-2 months off; 1-2mg SC daily (FDA dose: 2mg/day)
Meldingen uit de community: Well-respected in anti-aging and peptide communities as a 'real' peptide (FDA-approved). Users report noticeable visceral fat reduction within 8-12 weeks. Commonly compared to sermorelin and ipamorelin. Main concern: cost and daily injection requirement. Steady demand from the anti-aging crowd.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Tesamorelin for visceral fat reduction in HIV
Significantly reduced trunk fat and improved lipid profiles in large-scale RCT.
Tesamorelin and cognitive function
Improved executive function and verbal memory in adults with mild cognitive impairment or subjective cognitive complaints.
Tesamorelin effects on hepatic fat
Reduced liver fat and improved markers of NAFLD.
Growth hormone and tesamorelin in the treatment of HIV-associated lipodystrophy
Tesamorelin significantly reduced visceral adipose tissue in HIV-associated lipodystrophy, providing the basis for FDA approval as Egrifta.
Metabolic effects of a growth hormone-releasing factor in patients with HIV
Significant trunk fat reduction with improved triglyceride levels in NEJM published trial (Falutz et al.). Key basis study for FDA approval.
Tesamorelin effects on NAFLD and cognitive function in aging
Emerging data shows NAFLD fat reduction and cognitive improvement in aging populations. Tesamorelin's effects extend beyond HIV lipodystrophy to broader metabolic and neuroprotective applications.
Studies worden ter referentie vermeld. De meeste zijn uitgevoerd in dier- of celmodellen; de resultaten tonen geen veiligheid of werking bij mensen aan.
Tesamorelin … gave myself time to reset. During that cycle I experienced really good results … really good results
Anybody else experience side effects from tesamorelin? Starting my 3rd month I really noticed side effects. I feel like my head is swollen. I feel dizzy and I have almost passed out a few times. I'm not diabetic, but I feel like it's how a diabetic feels? I've occasionally had
I have been on Tesamorelin about 400-500mcg 6 nights on 1 night off per week and while luckily some side effects like my wrists aching and the aggression are going away, I am not sure how I should be eating to see any results. … I have been on Tesamorelin about 400-500mcg 6 nigh…
Based on 3 qualifying reports from 3 threads. 33 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Vragen en antwoorden die bij dit product zijn vastgelegd.
Both are GHRH analogs, but tesamorelin is a full 44-amino acid GHRH analog with a trans-3-hexenoic acid modification for DPP-4 resistance, while sermorelin is only the first 29 amino acids. Tesamorelin is FDA-approved (Egrifta) with specific clinical data on visceral fat reduction via CT imaging. Sermorelin has broader anti-aging clinic use. Tesamorelin is considered more potent for visceral fat specifically.
Yes — tesamorelin (GHRH pathway) and ipamorelin (ghrelin/GHS pathway) stimulate GH release through two independent receptor systems. This dual-pathway approach is studied for potentially amplified GH output compared to either compound alone. This is one of the most popular GH peptide stacks for targeted visceral fat reduction.
Published clinical protocols use 2mg SC daily continuously. The research community typically runs 3-6 month cycles with 1-2 month breaks. CT imaging studies showed visceral fat reduction within 8-12 weeks, with continued improvement through 6 months. Most anti-aging practitioners recommend monitoring IGF-1 levels periodically during use.
Both are GHRH analogs. Tesamorelin is more potent, has FDA approval, and has stronger clinical data. Sermorelin has a longer track record and lower cost.
Yes. Tesamorelin is FDA-approved as Egrifta® for reduction of excess abdominal fat in HIV-associated lipodystrophy.
Tesamorelin has higher synthesis costs and is the most potent GHRH analog available with robust Phase III clinical trial data. Its pharmaceutical pedigree commands premium pricing.
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