Sermorelin Acetate — 10mg
234.99€
Ipamorelin — 10mg
A growth hormone peptide so selective that researchers couldn't break its specificity at 200x the dose.
159.99€
Excl. btw 159.99€
- In Stock
- Evidence tier: Emerging
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
Uitsluitend voor laboratoriumonderzoek. Niet voor gebruik bij mens of dier.
Over Ipamorelin
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a pentapeptide (Aib-His-D-2Nal-D-Phe-Lys-NH2) growth hormone secretagogue that selectively activates ghrelin/GHS-R1a receptors on anterior pituitary somatotrophs. What makes it unique among GHRPs is its remarkable selectivity: it stimulates GH release with potency comparable to GHRP-6 but does not stimulate ACTH, cortisol, prolactin, or aldosterone secretion, even at doses 200-fold above the ED50 for GH release. This selectivity mirrors GHRH rather than other GHRP-receptor agonists. It also shows moderate resistance to metabolism with ~60-80% recovered intact.
Duidelijkheid van het mechanisme: Well-characterized
Tags
Belangrijkste punten
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Onderzoeksscore 7/10
78+ gepubliceerde studies in de dataset
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Bewijsniveau: Emerging
Emerging — Some human clinical data (post-surgical applications), extensive pharmacological characterization. The selectivity profile is well-established in clinical pharmacology studies. Less clinical trial data than sermorelin or tesamorelin for anti-aging applications.
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Gegevens bij mensen
Phase I/II human data (post-surgical GI recovery); extensive pharmacological characterization in humans
Opslag en hantering
Gevriesdroogd poeder: Room temperature or refrigerated
Na reconstitutie: Refrigerate; use within 30 days
Veiligheid en beperkingen
Onderzocht voor: Growth hormone optimization, Sleep quality improvement, Fat loss and body recomposition, Recovery from training, Anti-aging protocols
Gemelde aanvang: Sleep improvement within 1-2 weeks; body composition changes over 8-12 weeks
Gemelde duur: 8-16 weeks on, 4 weeks off; 200-300mcg SC 2-3x daily
Meldingen uit de community: Very clean profile — no hunger spikes (unlike GHRP-6), no cortisol elevation. Users report improved sleep quality first, then gradual body composition improvements. Most commonly stacked with CJC-1295 (no DAC) for the 'gold standard' GH peptide stack.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Kwaliteit en specificaties
Product details
- Productcode
- L-IPAM-10
- Beschikbaarheid
- In Stock
- Evidence tier
- Emerging
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Reconstitutiereferentie
- Bacteriostatisch water
- 2 mL
- Concentratie
- 5mg/mL (5mcg per unit). Standard 200mcg dose = 40 units (0.04mL).
- Spuit
- 29-31G insulin
Onderzoeksparameters
- Standaardhoeveelheid
- 200 µg
- Alternatieve hoeveelheid
- 300 µg
- Flacon
- 10 mg
- Schatting uit de dataset
- ~3.5 weeks at 200mcg 2x/day (1 vial of 10mg)
Laboratoriumrapport
- Laboratorium
- Janoshik Analytical
- Testdatum
- 2026-03-01
- Document
- Pdf niet bijgevoegd
Bekijk de wetenschap
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PMID 9849822
Lees de studie: Ipamorelin, the first selective growth hormone secretagogue (opent in een nieuw tabblad)
Ipamorelin, the first selective growth hormone secretagogue
First GHRP with selectivity for GH similar to GHRH; no ACTH/cortisol increase even at 200x the ED50 for GH release.
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PMID 9849822
Lees de studie: Pharmacological characterization of ipamorelin (opent in een nieuw tabblad)
Pharmacological characterization of ipamorelin
5-fold lower systemic clearance than GHRP-6; 60-80% recovered intact. Clean, dose-dependent GH release without desensitization.
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Ipamorelin in post-surgical GI recovery
Improved bowel function post-surgery in human clinical studies. One of the few GH secretagogues with human clinical trial data.
Studies worden ter referentie vermeld. De meeste zijn uitgevoerd in dier- of celmodellen; de resultaten tonen geen veiligheid of werking bij mensen aan.
Verder lezen
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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11 months agor/BodyHackGuide · Post
Ipamorelin … Tesamorelin + Ipamorelin … my recovery improved, sleep got deeper, and the stubborn visceral fat around my midsection finally started moving
Based on 1 qualifying reports from 1 threads. 21 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Vragen over Ipamorelin
Vragen en antwoorden die bij dit product zijn vastgelegd.
Ipamorelin is the most selective GH secretagogue identified. Unlike GHRP-6 (which causes intense hunger) or GHRP-2 (which elevates cortisol and prolactin), ipamorelin stimulates growth hormone release without significantly affecting cortisol, prolactin, ACTH, or aldosterone — even at doses 200x above the effective dose. This selectivity makes it the cleanest option for GH research.
Yes — ipamorelin (ghrelin receptor pathway) and sermorelin or CJC-1295 (GHRH receptor pathway) work through two completely different receptor systems on the pituitary. Published research suggests dual-pathway stimulation produces greater GH release than either alone. The ipamorelin + CJC-1295 (no DAC) combination is one of the most studied GH peptide stacks in the research community.
Most research protocols administer ipamorelin before bed on an empty stomach (2-3 hours post-meal) to amplify the natural nocturnal GH pulse. Some protocols include a second dose upon waking, also fasted. GH release is blunted by food intake (particularly carbohydrates and fats), so timing around meals matters for optimal pulsatile response.
Beoordelingen
Er zijn nog geen beoordelingen voor dit product.
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Tesamorelin — 10mg
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