BPC-157 — 5mg
109.99€
LL-37 — 10mg
The sole cathelicidin antimicrobial peptide in the human immune system, capable of forming physical pores in bacterial membranes.
139.99€
Netto 139.99€
- In Stock
- Evidence tier: Experimental
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
Wyłącznie do badań laboratoryjnych. Nie do stosowania u ludzi ani zwierząt.
O produkcie LL-37
LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It is produced by immune cells, epithelial cells, and other tissues as a first-line defense against pathogens. Beyond direct antimicrobial activity, published research documents LL-37's roles in immune cell recruitment, inflammation modulation, wound healing, and biofilm disruption. It sits at the intersection of antimicrobial defense and tissue repair — two processes the body rarely separates.
LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It is produced by immune cells, epithelial cells, and other tissues as a first-line defense against pathogens. Beyond direct antimicrobial activity, published research documents LL-37's roles in immune cell recruitment, inflammation modulation, wound healing, and biofilm disruption. It sits at the intersection of antimicrobial defense and tissue repair — two processes the body rarely separates.
LL-37 is the sole human cathelicidin antimicrobial peptide, a 37-amino acid alpha-helical peptide derived from proteolytic cleavage of the 18kDa precursor hCAP-18. It operates through multiple mechanisms: direct antimicrobial action via membrane disruption (oligomerizes to form transmembrane pores in bacterial membranes), LPS/endotoxin neutralization, chemotaxis of immune cells (neutrophils, monocytes, T-cells), inhibition of neutrophil apoptosis, stimulation of angiogenesis and tissue regeneration, and modulation of cytokine release (IL-8, TNF-alpha). Its production is upregulated by vitamin D3, bacterial products, and inflammation.
Poznanie mechanizmu: Well-characterized
Tagi
Najważniejsze informacje
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Ocena badań 6/10
200+ opublikowanych badań w zbiorze danych
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Poziom dowodów: Experimental
Experimental — Well-characterized as a natural immune peptide with extensive in-vitro and animal data. Clinical research ongoing for wound healing and infection. No completed human RCTs for injectable use. The mechanism is well-established but therapeutic application is early-stage.
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Poziom praktyczny: Emerging
Good mechanistic understanding. Antimicrobial + wound healing data. Limited clinical application studies.
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Dane u ludzi
In-vitro human cell data
Przechowywanie i obchodzenie się
Proszek liofilizowany: Room temp or refrigerated
Po rekonstytucji: Refrigerate, use within 30 days
Bezpieczeństwo i ograniczenia
Badany w kontekście: Immune defense, Biofilm disruption, Wound healing, Chronic infections, Antimicrobial defense
Zgłaszany początek działania: Immune effects within days; chronic infection management over 2-4 weeks
Zgłaszany czas trwania: 2-4 weeks; 100-200mcg SC daily
Relacje społeczności: Niche peptide used mainly in chronic illness communities (Lyme, long COVID, CFS). Positive reports for chronic infection management. Key concern: LL-37 overexpression is implicated in psoriasis and lupus, so use should be time-limited. Contraindicated in active autoimmune conditions. Low doses recommended — this is potent.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Jakość i specyfikacja
Product details
- Kod produktu
- L-LL37-10
- Dostępność
- In Stock
- Evidence tier
- Experimental
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Dane do rekonstytucji
- Woda bakteriostatyczna
- 2 mL
- Stężenie
- 25mcg per unit. 100mcg dose = 4 units.
- Strzykawka
- 29-31G insulin
Parametry badawcze
- Ilość standardowa
- 200 µg
- Ilość alternatywna
- 100 µg
- Fiolka
- 10 mg
- Szacunek ze zbioru danych
- 1 vial lasts ~7 weeks at 200mcg/day
Raport laboratoryjny
- Laboratorium
- Janoshik Analytical
- Data badania
- 2026-03-01
- Dokument
- PDF nie jest dołączony
Zobacz badania
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PMID 16352721
Czytaj badanie: LL-37, the only human member of the cathelicidin family (otwiera się w nowej karcie)
LL-37, the only human member of the cathelicidin family
Comprehensive review of LL-37's antimicrobial, immunomodulatory, and wound healing properties.
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PMID 18036595
Czytaj badanie: Cathelicidin antimicrobial peptide in wound healing (otwiera się w nowej karcie)
Cathelicidin antimicrobial peptide in wound healing
LL-37 promotes wound vascularization and re-epithelialization.
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PMID 20049649
Czytaj badanie: Cathelicidin LL-37: a multitask antimicrobial peptide (otwiera się w nowej karcie)
Cathelicidin LL-37: a multitask antimicrobial peptide
LL-37 is antimicrobial, chemoattractant, anti-apoptotic, and angiogenic; production is regulated by vitamin D3.
Badania podano w celach informacyjnych. Większość przeprowadzono na modelach zwierzęcych lub komórkowych; ich wyniki nie dowodzą bezpieczeństwa ani działania u ludzi.
Dalsza lektura
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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1 year agor/badbreath · Post
LL-37 … what worked for me is LL-37 … I might have actually beaten chronic bad breath
Based on 1 qualifying reports from 1 threads. 12 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Pytania o LL-37
Pytania i odpowiedzi zapisane dla tego produktu.
LL-37 interferes with bacterial quorum sensing (communication) and destabilizes the extracellular matrix that protects biofilm communities. Published research shows LL-37 can penetrate and disrupt established biofilms at concentrations where conventional antibiotics fail.
LL-37 has direct antimicrobial activity (kills bacteria) in addition to immune signaling, unlike purely signaling peptides like Thymosin Alpha-1.
The only cathelicidin antimicrobial peptide produced by the human body. It serves as part of the innate immune defense system.
Opinie
Ten produkt nie ma jeszcze opinii.
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