NAD+ — 500mg
249.99€
MOTS-c — 10mg
The first peptide discovered to be encoded by mitochondrial DNA rather than nuclear DNA, shown to activate the same metabolic pathways as physical exercise.
189.99€
Netto 189.99€
- In Stock
- Evidence tier: Emerging
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
Wyłącznie do badań laboratoryjnych. Nie do stosowania u ludzi ani zwierząt.
O produkcie MOTS-c
MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial genome's 12S rRNA gene. It is the first mitochondrial-encoded peptide shown in published research to regulate nuclear gene expression — making it a signaling molecule between mitochondria and the cell nucleus. Researchers study MOTS-c for its documented effects on metabolic homeostasis, exercise physiology, and cellular energy production.
MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial genome's 12S rRNA gene. It is the first mitochondrial-encoded peptide shown in published research to regulate nuclear gene expression — making it a signaling molecule between mitochondria and the cell nucleus. Researchers study MOTS-c for its documented effects on metabolic homeostasis, exercise physiology, and cellular energy production.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino acid peptide encoded by the mitochondrial genome (12S rRNA gene). It is the first mitochondrial-derived peptide (MDP) shown to regulate nuclear gene expression. In response to metabolic stress or exercise, MOTS-c translocates to the nucleus where it regulates antioxidant response element (ARE) genes, activates AMPK signaling, enhances skeletal muscle glucose uptake via GLUT4 translocation, increases fatty acid oxidation, and improves mitochondrial respiration. Functions as an exercise mimetic by activating exercise-responsive gene programs.
Poznanie mechanizmu: Well-characterized (AMPK activation, nuclear translocation, ARE gene regulation)
Tagi
Najważniejsze informacje
-
Ocena badań 7/10
200+ opublikowanych badań w zbiorze danych
-
Poziom dowodów: Emerging
Experimental — Highly promising preclinical data. Limited human data (small studies, mostly observational correlations). The mitochondrial origin and exercise-mimetic mechanism are scientifically novel and well-published, but clinical translation is early.
-
Poziom praktyczny: Emerging
Discovered 2015 at USC. Accelerating publication rate. Exercise-mimetic properties confirmed in animal models. Limited human data.
-
Dane u ludzi
Small observational studies; exercise correlation data
Przechowywanie i obchodzenie się
Proszek liofilizowany: Room temp or refrigerated
Po rekonstytucji: Refrigerate at 2-8°C, use within 14 days
Etapy rekonstytucji ze zbioru danych
- Clean. Remove flip-top cap and swab rubber stopper with alcohol.
- Draw water. Draw 1mL of bacteriostatic water into syringe.
- Inject water. Insert needle through stopper and slowly inject water down the side of the vial.
- Dissolve. Gently swirl until fully dissolved. Solution should be clear.
- Label. Label vial with date and concentration (10mg/mL). Refrigerate immediately.
- Dose. For 5mg dose: draw 0.5mL (50 units). For 10mg dose: draw full 1mL. Inject SC in abdomen.
Bezpieczeństwo i ograniczenia
Badany w kontekście: Exercise mimetic effects, Insulin sensitivity, Metabolic regulation, Mitochondrial function, Longevity/healthspan
Zgłaszany początek działania: 1-2 weeks for subjective energy changes; 4+ weeks for metabolic effects
Zgłaszany czas trwania: 4-8 week cycles; some protocols run 4-6 weeks with breaks
Relacje społeczności: Mixed but positive. Some users report clear energy improvement and better workout recovery. Others say effects are subtle without biomarker tracking. Often stacked with SS-31 for "mitochondrial stack." Best results reported with consistent exercise alongside.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Jakość i specyfikacja
Product details
- Kod produktu
- L-MOTSC-10
- Dostępność
- In Stock
- Evidence tier
- Emerging
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Dane do rekonstytucji
- Woda bakteriostatyczna
- 1 mL
- Stężenie
- 10mg/mL when reconstituted with 1mL. 5mg dose = 0.5mL (50 units). 10mg dose = 1mL (100 units).
- Strzykawka
- 29-31G insulin syringe (1mL capacity recommended)
Parametry badawcze
- Ilość standardowa
- 5000 µg
- Ilość alternatywna
- 10000 µg
- Fiolka
- 10 mg
- Szacunek ze zbioru danych
- ~1 week at 10mg 3x/week (1 vial), ~2 weeks at 5mg 3x/week
Raport laboratoryjny
MOTS-c 10mg — Certificate of Analysis
- Laboratorium
- Janein Labs
- Data badania
- 2026-03-01
- Status
- Passed
- Odnotowana czystość
- 99.0%
- Endotoksyny
- <0.5 EU/mg
- Dokument
- PDF nie jest dołączony
Zobacz badania
-
PMID 25738459
Czytaj badanie: MOTS-c discovery and metabolic effects (otwiera się w nowej karcie)
MOTS-c discovery and metabolic effects
Identified MOTS-c as a mitochondrial-derived peptide that regulates metabolic homeostasis and targets insulin resistance.
-
PMID 30135581
Czytaj badanie: MOTS-c and exercise (otwiera się w nowej karcie)
MOTS-c and exercise
MOTS-c levels increase with exercise and mediate some exercise-induced metabolic adaptations.
-
PMID 33082511
Czytaj badanie: MOTS-c and COVID-19 resilience (otwiera się w nowej karcie)
MOTS-c and COVID-19 resilience
Higher endogenous MOTS-c levels associated with better metabolic resilience in older adults.
Badania podano w celach informacyjnych. Większość przeprowadzono na modelach zwierzęcych lub komórkowych; ich wyniki nie dowodzą bezpieczeństwa ani działania u ludzi.
Dalsza lektura
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
-
6 months agor/BodyHackGuide · Post
I got what I would describe as almost an intense focus
-
11 months agor/Peptidesource · Post
Mots C … 1st dose … headaches whenever I inject Mots C. And noticed my dandruff flare up since my 1st dose.
Based on 2 qualifying reports from 2 threads. 23 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Pytania o MOTS-c
Pytania i odpowiedzi zapisane dla tego produktu.
Yes. MOTS-c is encoded in the mitochondrial genome and naturally produced by cells. Levels increase with exercise and decline with age.
A compound that activates some of the same cellular pathways as physical exercise — particularly AMPK activation and metabolic adaptation. MOTS-c is the most studied mitochondrial exercise mimetic.
Growing mainstream media coverage, accelerating research publication rate, and endorsement by prominent longevity researchers have driven rapid demand growth.
Opinie
Ten produkt nie ma jeszcze opinii.
Powiązane produkty
-
-
Epithalon — 10mg
239.99€
-
SS-31 — 10mg
199.99€
Jak działa zamawianie
Dane produktu, źródła i zamówienie pozostają ze sobą powiązane.
-
Wybierz związek
Wybierz związek i rozmiar fiolki w katalogu.
-
Sprawdź informacje o produkcie
Otwórz szczegóły produktu i powiązane badania.
-
Zachowaj źródła
Zapisz źródła do swojej dokumentacji.
Dlaczego zamawiać w PeptidesEuro
Profile związków
Struktura, dostępne rozmiary i uwagi dotyczące obchodzenia się w jednym miejscu.
Źródła badań
Strony produktów prowadzą do badań dotyczących każdego związku.
Jedna historia zamówień
Zamówienia i ich szczegóły pozostają na Twoim koncie.
Przejrzyste dane produktu
Cena, dostępność i podatek przy każdym produkcie.
PeptidesEuro is a research materials supplier operated by Pepticore LLC. We provide high-purity peptides and research compounds for in-vitro laboratory and scientific research purposes. All products are sold strictly for research use only and are not intended for human or animal consumption.
No. All products sold through meimx.com are intended strictly for in-vitro laboratory and scientific research purposes only. They are not intended for human or animal consumption, injection, ingestion, inhalation, or any form of administration to living organisms. By purchasing from PeptidesEuro, you acknowledge and agree to these terms as outlined in our Terms of Service.
No. Our products have not been evaluated, approved, or authorized by the U.S. Food and Drug Administration (FDA) or any other regulatory body. They are not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. PeptidesEuro is not a compounding pharmacy or outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act.
No. PeptidesEuro does not provide medical advice, treatment recommendations, or dosing instructions. Any information on our website, including product descriptions and referenced research, is provided for educational and informational purposes only. If you have medical questions, please consult a licensed healthcare provider.
Research Use Only means that our products are sold exclusively as reference standards and research materials for use in laboratory and scientific research settings. Purchasers agree to use all products solely for legitimate research purposes in compliance with all applicable laws and regulations.
Gotowy, by zamówić MOTS-c?
Przeglądaj katalog albo odpowiedz na jedno pytanie w wyszukiwarce produktów.