Sermorelin Acetate — 10mg
234.99€
A growth hormone peptide so selective that researchers couldn't break its specificity at 200x the dose.
159.99€
Netto 159.99€
Wyłącznie do badań laboratoryjnych. Nie do stosowania u ludzi ani zwierząt.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts through the ghrelin/GHS receptor to stimulate pulsatile growth hormone release from the pituitary. It is distinguished from other GH secretagogues by its high selectivity — published research shows it stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it the cleanest GH secretagogue in the research peptide category.
Ipamorelin is a pentapeptide (Aib-His-D-2Nal-D-Phe-Lys-NH2) growth hormone secretagogue that selectively activates ghrelin/GHS-R1a receptors on anterior pituitary somatotrophs. What makes it unique among GHRPs is its remarkable selectivity: it stimulates GH release with potency comparable to GHRP-6 but does not stimulate ACTH, cortisol, prolactin, or aldosterone secretion, even at doses 200-fold above the ED50 for GH release. This selectivity mirrors GHRH rather than other GHRP-receptor agonists. It also shows moderate resistance to metabolism with ~60-80% recovered intact.
Poznanie mechanizmu: Well-characterized
78+ opublikowanych badań w zbiorze danych
Emerging — Some human clinical data (post-surgical applications), extensive pharmacological characterization. The selectivity profile is well-established in clinical pharmacology studies. Less clinical trial data than sermorelin or tesamorelin for anti-aging applications.
Phase I/II human data (post-surgical GI recovery); extensive pharmacological characterization in humans
Proszek liofilizowany: Room temperature or refrigerated
Po rekonstytucji: Refrigerate; use within 30 days
Badany w kontekście: Growth hormone optimization, Sleep quality improvement, Fat loss and body recomposition, Recovery from training, Anti-aging protocols
Zgłaszany początek działania: Sleep improvement within 1-2 weeks; body composition changes over 8-12 weeks
Zgłaszany czas trwania: 8-16 weeks on, 4 weeks off; 200-300mcg SC 2-3x daily
Relacje społeczności: Very clean profile — no hunger spikes (unlike GHRP-6), no cortisol elevation. Users report improved sleep quality first, then gradual body composition improvements. Most commonly stacked with CJC-1295 (no DAC) for the 'gold standard' GH peptide stack.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Ipamorelin, the first selective growth hormone secretagogue
First GHRP with selectivity for GH similar to GHRH; no ACTH/cortisol increase even at 200x the ED50 for GH release.
Pharmacological characterization of ipamorelin
5-fold lower systemic clearance than GHRP-6; 60-80% recovered intact. Clean, dose-dependent GH release without desensitization.
Ipamorelin in post-surgical GI recovery
Improved bowel function post-surgery in human clinical studies. One of the few GH secretagogues with human clinical trial data.
Badania podano w celach informacyjnych. Większość przeprowadzono na modelach zwierzęcych lub komórkowych; ich wyniki nie dowodzą bezpieczeństwa ani działania u ludzi.
Ipamorelin … Tesamorelin + Ipamorelin … my recovery improved, sleep got deeper, and the stubborn visceral fat around my midsection finally started moving
Based on 1 qualifying reports from 1 threads. 21 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Pytania i odpowiedzi zapisane dla tego produktu.
Ipamorelin is the most selective GH secretagogue identified. Unlike GHRP-6 (which causes intense hunger) or GHRP-2 (which elevates cortisol and prolactin), ipamorelin stimulates growth hormone release without significantly affecting cortisol, prolactin, ACTH, or aldosterone — even at doses 200x above the effective dose. This selectivity makes it the cleanest option for GH research.
Yes — ipamorelin (ghrelin receptor pathway) and sermorelin or CJC-1295 (GHRH receptor pathway) work through two completely different receptor systems on the pituitary. Published research suggests dual-pathway stimulation produces greater GH release than either alone. The ipamorelin + CJC-1295 (no DAC) combination is one of the most studied GH peptide stacks in the research community.
Most research protocols administer ipamorelin before bed on an empty stomach (2-3 hours post-meal) to amplify the natural nocturnal GH pulse. Some protocols include a second dose upon waking, also fasted. GH release is blunted by food intake (particularly carbohydrates and fats), so timing around meals matters for optimal pulsatile response.
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PeptidesEuro is a research materials supplier operated by Pepticore LLC. We provide high-purity peptides and research compounds for in-vitro laboratory and scientific research purposes. All products are sold strictly for research use only and are not intended for human or animal consumption.
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