NAD+ — 500mg
249.99€
Semax — 10mg
The nootropic peptide with decades of clinical research across cognitive performance, neuroprotection, and BDNF upregulation.
204.99€
Netto 204.99€
- In Stock
- Evidence tier: Emerging
- Format: Lyophilized
- Purity: 99.3%
- Vial size: 10mg
Wyłącznie do badań laboratoryjnych. Nie do stosowania u ludzi ani zwierząt.
O produkcie Semax
Semax Lyophilized — a synthetic heptapeptide based on the ACTH(4-10) fragment, in lyophilized powder form for subcutaneous administration. Originally developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Widely studied for its effects on BDNF expression, cognitive function, and neuroprotection.
Synthetic heptapeptide based on the ACTH(4-10) fragment. Approved in Russia as a nootropic since the 1990s. Studied for BDNF expression, cognitive function, and neuroprotection.
Heptapeptide analog of ACTH(4-7) with C-terminal Pro-Gly-Pro extension. Increases BDNF protein levels (1.4-fold) and trkB tyrosine phosphorylation (1.6-fold), upregulates BDNF mRNA (3-fold) and trkB mRNA (2-fold) in hippocampus, modulates serotonergic and dopaminergic neurotransmission, activates MAPK/ERK signaling cascades.
Poznanie mechanizmu: Well-characterized (BDNF upregulation, trkB phosphorylation, MAPK/ERK signaling)
Tagi
Najważniejsze informacje
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Ocena badań 7/10
300+ opublikowanych badań w zbiorze danych
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Poziom dowodów: Emerging
Approved in Russia since 1990s. Multiple animal and human studies on BDNF, cognitive function, and neuroprotection.
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Poziom praktyczny: Established
Approved prescription medication in Russia. Clinical data for stroke recovery and cognition. Not FDA-approved in US.
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Dane u ludzi
Russian clinical trials and prescription use data; limited Western RCTs
Przechowywanie i obchodzenie się
Proszek liofilizowany: Room temp or refrigerated
Po rekonstytucji: Refrigerate at 2-8°C, use within 14-21 days
Etapy rekonstytucji ze zbioru danych
- Prepare. If using pre-made nasal spray, skip to step 5. For powder reconstitution: clean vial top with alcohol.
- Add saline. Draw 2mL bacteriostatic saline (NOT water) and inject slowly into vial.
- Dissolve. Gently swirl until fully dissolved. Solution should be clear.
- Transfer. Transfer solution to a sterile nasal spray bottle using a syringe. Each spray ≈ 0.1mL (200mcg at 5mg/mL).
- Administer. Tilt head back slightly. Insert nozzle into nostril and spray once. Alternate nostrils. Standard dose: 1-3 sprays (200-600mcg) 2-3x daily.
- Store. Refrigerate nasal spray. Use within 14-21 days after reconstitution.
Bezpieczeństwo i ograniczenia
Badany w kontekście: Cognitive enhancement, Stroke recovery, BDNF modulation, Neuroprotection, ADHD symptom management
Zgłaszany początek działania: 5-15 minutes intranasal; 15-30 minutes subcutaneous
Zgłaszany czas trwania: 2-4 week cycles on, 2 weeks off (Russian clinical protocol: 10-20 days)
Relacje społeczności: Polarizing. Responders describe "clean stimulant without jitters" — improved focus, verbal fluency, and working memory. Non-responders notice nothing. Some report increased irritability at higher doses. Quality varies significantly between vendors. N-Acetyl Semax Amidate considered most potent form.
For research and educational use only. Source values are reproduced from the current PeptidesEuro content dataset and are not medical advice.
Jakość i specyfikacja
Product details
- Kod produktu
- L-SEMAX-10
- Dostępność
- In Stock
- Evidence tier
- Emerging
- Format
- Lyophilized
- Purity
- 99.3%
- Vial size
- 10mg
Dane do rekonstytucji
- Woda bakteriostatyczna
- 2 mL
- Stężenie
- Nasal spray: ~200mcg per spray. If reconstituting from powder: 5mg/mL with 2mL bacteriostatic saline.
- Strzykawka
- Nasal spray bottle (not syringe)
Parametry badawcze
- Ilość standardowa
- 500 µg
- Ilość alternatywna
- 1000 µg
- Fiolka
- 10 mg
- Szacunek ze zbioru danych
- 1 vial lasts ~20 days at 500mcg/day
Raport laboratoryjny
Semax Lyophilized 10mg — Certificate of Analysis
- Laboratorium
- Janoshik Analytical
- Data badania
- 2026-03-15
- Status
- Passed
- Odnotowana czystość
- 99.3%
- Endotoksyny
- <0.5 EU/mg
- Dokument
- PDF nie jest dołączony
Zobacz badania
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PMID 16996037
Czytaj badanie: Semax neuroprotective effects in ischemia (otwiera się w nowej karcie)
Semax neuroprotective effects in ischemia
Demonstrated neuroprotection and improved cognitive outcomes post-ischemic injury.
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PMID 17186529
Czytaj badanie: Semax and BDNF expression (otwiera się w nowej karcie)
Semax and BDNF expression
Significantly increased BDNF mRNA expression in rat hippocampus and cortex.
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PMID 22036090
Czytaj badanie: Semax prevents learning and memory impairment caused by transient cerebral ischemia (otwiera się w nowej karcie)
Semax prevents learning and memory impairment caused by transient cerebral ischemia
Semax administration prevented spatial learning and memory impairment in rats following cerebral ischemia, supporting neuroprotective applications.
Badania podano w celach informacyjnych. Większość przeprowadzono na modelach zwierzęcych lub komórkowych; ich wyniki nie dowodzą bezpieczeństwa ani działania u ludzi.
Dalsza lektura
Community evidence
- Source window English Reddit Updated 13 Aug 2026 · 2-year window
- Coverage confidence Low Confidence in the available community sample
- Distribution Pending Not enough data for a distribution.
Selected reports
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1y agor/iih · Comment
... Semax definitely helped make me feel “normal” throughout the day. I have just run out and I can feel a huge difference from coming off. Will definitely be ordering more
Based on 1 qualifying reports from 1 threads. 35 candidates excluded as duplicates, promotion, deleted content, or lacking concrete personal experience. Reddit self-reports are not medical evidence or proof of causation.
Pytania o Semax
Pytania i odpowiedzi zapisane dla tego produktu.
Intranasal is the standard route used in Russian clinical practice and most research protocols. It provides rapid onset (5-15 minutes) and bypasses first-pass metabolism. Subcutaneous injection is less common but used by some researchers. The nasal spray format is preferred for convenience and established dosing protocols.
No. Semax is supplied as a ready-to-use nasal spray — no reconstitution or injections required.
Semax is an approved prescription medication in Russia for stroke recovery and cognitive disorders. It is sold for research purposes in the US.
Opinie
Ten produkt nie ma jeszcze opinii.
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